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Updated: Mar 11, 2021

Achieve the Dream of Safe Motherhood

All you need to know about IVF and ICSI Is there a difference between them?

Delayed childbearing is one of the most important problems that plague the lives of spouses, especially at the beginning of their married life. If the occurrence of pregnancy is delayed for several months after marriage, the spouses resort to consulting a doctor to find out the cause and take the necessary immediately. Usually the doctor indicates to the spouses the necessity of medical intervention to increase the chances of childbearing by performing operations such as IVF and ICSI, so how are these operations performed and is there a difference between them?

When do we resort to the IVF and ICSI process?

Delayed childbearing occurs as a result of health problems in the husband or wife, and it may also be delayed without a specific reason. The IVF and ICSI process are among the modern medical methods that help solve the problem of delayed childbearing, and the obstetrician-gynecologist recommends the appropriate process for each case.

When is IVF performed?

● Infertility without cause.

● Fallopian tube adhesions.

● Endometriosis.

● Polycystic ovary disease.

● uterine fibroids.

● Ovarian failure or premature discontinuation.

● Birth defects in the womb, such as a cleft uterus.

● If the wife is over 35 years old.

When is IVF and ICSI performed together?

Recent scientific studies recommend adding ICSI to IVF in all cases in general, and especially in cases of infertility in the husband, such as the following cases:

● Low sperm count.

● Increase the rate of abnormalities in the sperm.

● The occurrence of ejaculation outside the womb.

● poor sperm motility.

● In the event that sperm is completely absent in the semen, a testicular tissue biopsy is performed.

● A blockage in the ducts of the man's reproductive system.

● Genetic diseases of the husband or wife, as these techniques help to select the best types of eggs and sperms for fertilization.

What is the difference between IVF and ICSIThe ICSI

process is one of the modern techniques that has been added to the IVF process, as the ICSI process is a step in the IVF process, and the IVF process may be performed separately without microscopic injection.Recent scientific research has shown that adding an ICSI step to IVF children greatly increased the success rate of the operation and increased the chances of childbearing, especially in cases of infertility in the husband.

IVF process

During the IVF process, a number of eggs are withdrawn and placed in an incubator outside the womb with a large number of sperm, and the fertilization process is left to take place normally.


On the other hand, some doctors resort to using ICSI with IVF to increase the chance of pregnancy, as the doctor selects a sperm and tries to complete the insemination under a microscope.Many scientific studies have indicated that the success rates of IVF and ICSI together are much higher than that of IVF only, and fertilization success rates by IVF reach from 70% to 85%.

Steps in the process of IVF and ICSI

Preparing the mother for the month prior to the ICSI procedure begins with several steps as follows:

1. A vaginal ultrasound during the first or second day of the menstrual cycle.

2. Medicines to stimulate ovulation are used by intramuscular injection and continue to monitor the growth of eggs and measure their size day after day with a vaginal ultrasound.

3. After reaching a certain number of eggs inside the ovary to the required size, the hcg hormone is given by intramuscular injection to push the eggs out of the follicles.

4. Under the influence of complete anesthesia, the doctor guides a needle into the vagina using an ultrasound device and withdraws the fully grown ova out of the uterus.

5. The eggs are fertilized with sperm outside the womb, and the embryos are kept in a suitable environment for a period of 3 to 5 days.

6. After the embryo incubation period ends in the laboratory, the best and most healthy embryos are selected and reintroduced into the mother's womb until she continues to grow normally.

7. The embryos are inserted without full anesthesia, and this step is usually painless at all.

8. The mother lies on her back for about two hours, then she is allowed to move and practice her usual activities normally.

Tips for planning to IVF and ICSI babies

and indicators of success The process of IVF and ICSI seems to be somewhat complicated, as it consists of several stages and may cause tension and anxiety, but with the high rates of these operations, the success rates have also increased significantly. Among the success factors for IVF and ICSI:

● Psychological calm, freedom from stress and anxiety.

● Confidence in the treating physician, adherence to the follow-up schedule, and taking medications on time precisely before the operation.

● Adherence to the instructions after the procedure, as it is necessary to rest and take pregnancy stabilizers such as progesterone for at least two weeks after the ICSI.

● Egg efficiency: the wife's age affects the fertility and efficiency of the eggs, which may reduce the chance of the success of the fertilization process. The highest age stage in the fertility rate is from 24 to 35 years.

● Preparing the uterus to receive the fetus: the health of the endometrium affects the success rate of the operation, and the presence of fibroids, for example, or appendages in the uterine wall may reduce the chance of pregnancy and completion.

● Infection of the mother with some immune diseases creates immune bodies and causes a miscarriage, and in such cases the doctor may prescribe immunosuppressive drugs to increase the chances of completing the pregnancy

The effect of IVF and ICSI babies on the child's intelligence and development

Many wonder about the effect of IVF and ICSI on the child's growth and mental and physical development, and this point has raised a lot of scientific research.The incidence of birth defects if a pregnancy occurs naturally ranges from 1.5% to 3% only, and this percentage does not differ much from the percentage of birth defects in the case of pregnancy using modern technologies such as IVF or ICSI.

Complications of IVF and ICSI IVF and ICSI

are safe operations in general, but there are some minor complications that the mother may face, such as:

● Ovarian hyperstimulation: only 10% of women experience ovarian hyperstimulation as a side effect of the stimulation drugs that the mother takes during the egg preparation period, some cases may require hospitalization.

● The increase in the number of twins: The pregnancy may occur in more than one twin in some cases, and with the increase in the number of twins, the risks of pregnancy and the chances of miscarriage increase, and the doctor may resort to intervention to terminate the growth of a number of fetuses.

● Rare complications that occur during re-injection of the fertilized egg into the uterus, such as a bladder or intestine wound, pelvic infection, or small clots.

● The possibility of premature labor may increase in ICSI pregnancies than normal pregnancies.


Fact Sheet: What is intracytoplasmic sperm injection (ICSI)?

Ovarian Stimulation and Monitoring


The Success Rate and Factors Affecting the Outcome of Assisted Reproductive Treatment in Subfertile Men

How is difference between IVF and ICSI

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